Thermo Fisher Scientific DNAJC13 Polyclonal Antibody
DNAJC13 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 인간과 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 4°C에서 보관하며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1175 to 1225 of human DnaJ homolog subfamily C member 13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70, regulating protein conformation at membrane sites and playing a role in intracellular trafficking. DNAJC13 co-localizes with endosomal system markers and is involved in membrane trafficking through early endosomes but not degradative organelles. It also regulates intracellular trafficking of the epidermal growth factor receptor (EGFR).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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