Thermo Fisher Scientific RCC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RCC1. Recombinant protein control fragment (Product #RP-94479). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RCC1,uniProtId:P18754-1,ncbiNodeId:9606,antigenRange:17-96,antigenLength:421,antigenImageFileName:PA5-55658_RCC1_P18754-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55658_RCC1_P18754-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646423

Product Specific Information

Immunogen sequence: IPKSKKVKVS HRSHSTEPGL VLTLGQGDVG QLGLGENVME RKKPALVSIP EDVVQAEAGG MHTVCLSKSG QVYSFGCNDE

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Target Information

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.