Thermo Fisher Scientific WFDC1 Polyclonal Antibody
Human WFDC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원 기반으로 제조되었으며, Affinity Chromatography로 정제되었습니다. PBS buffer에 2% sucrose 및 0.09% sodium azide 포함, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human WFDC1 (aa 35–84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577196 |
Product Specific Information
Peptide sequence:
WKRALPARLA EKSRAEEAGA PGGPRQPRAD RCPPPPRTLP PGACQAARCQ
Sequence homology:
- Dog: 91%
- Human: 100%
Target Information
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, functioning as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, originally identified as a secreted growth inhibitor.
This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers such as prostate, breast, hepatocellular cancers, and Wilms' tumor. Due to its chromosomal location and possible growth inhibitory properties, this gene is suggested to act as a tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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