Thermo Fisher Scientific Angiopoietin 1 Polyclonal Antibody
Angiopoietin 1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 및 마우스 반응성을 가집니다. Western blot에 적합하며, 혈관 발달 및 안정성 연구에 유용합니다. 단백질 A 및 항원 친화 크로마토그래피로 정제되었습니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 374–402 from the C-terminal region of human ANGPT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.34 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541454 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, and porcine species based on sequence homology.
Target Information
Angiopoietins are key regulators of vascular development and angiogenesis. They bind to endothelial cell-specific tyrosine-protein kinase receptors, activating them through tyrosine phosphorylation. Angiopoietin 1 plays a critical role in maintaining vessel integrity, mediating interactions between the endothelium and surrounding matrix, and contributing to blood vessel maturation and stability. It may also be involved in early heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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