Thermo Fisher Scientific PPAPDC3 Polyclonal Antibody
Human PPAPDC3 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 근육 조직 연구 및 세포 분화 관련 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PPAPDC3 Polyclonal Antibody
Thermo Fisher Scientific PPAPDC3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PPAPDC3 (Recombinant protein control fragment, Product #RP-107737) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664108 |
Product Specific Information
Immunogen sequence:
GPYETSPSLLD YLTMDIYAFP AGHASRAAMV SK
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 97%
Target Information
PPAPDC3 (Phosphatidic acid phosphatase type 2 domain containing 3), also known as nuclear envelope transmembrane protein 39 (NET39), was identified in an in silico screen for secreted or membrane proteins. It belongs to the PAP2 superfamily of phosphatases and haloperoxidases.
PPAPDC3 acts as a negative regulator of myoblast differentiation by diminishing the activity of mTOR. It is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation. Overexpression represses myogenesis, while knockdown promotes differentiation, indicating its regulatory role in myogenesis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음, OCR 텍스트만 통합 완료)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.