Thermo Fisher Scientific SLC7A11 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SLC7A11 for IHC(P) applications. Recognizes cystine/glutamate transporter XCT. High species homology and antigen affinity purified. Supplied as liquid, unconjugated, 1 mg/mL in PBS with sodium azide.
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Applications
- Immunohistochemistry (Paraffin) [IHC(P)]: Tested dilution 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from N-terminus of human SLC7A11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550511 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Orangutan, Gibbon (100%); Monkey, Marmoset (95%); Horse (89%); Rat, Dog, Hamster (84%).
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
SLC7A11 (XCT) is a member of a heteromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 mediates Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression in primary gliomas is associated with neuronal cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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