
Thermo Fisher Scientific ASB2 Monoclonal Antibody (OTI4C2), TrueMAB
ASB2 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(P)에서 검증됨. 인체 유래 단백질(aa 1-300)을 면역원으로 사용. 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–300 of human ASB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full-length sequences are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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