Thermo Fisher Scientific MAP1LC3B2 Polyclonal Antibody
MAP1LC3B2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ICC/IF 및 ELISA에 사용 가능하며, Protein G 정제 및 PBS/glycerol buffer로 보관됩니다. 오토파지 및 미토파지 연구에 적합합니다.
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Thermo Fisher Scientific MAP1LC3B2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein (1–47 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092236 |
Target Information
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy, regulating mitochondrial quantity and quality by eliminating excess or damaged mitochondria to maintain cellular energy balance and prevent ROS overproduction. Upon cellular stress and mitochondrial fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes for clearance. LC3 proteins are involved in phagophore membrane elongation, while GABARAP/GATE-16 subfamily proteins are essential for autophagosome maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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