Thermo Fisher Scientific TTI2 Polyclonal Antibody
TTI2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액과 40% 글리세롤 포함. 인간 시료 반응성으로 연구용에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TTI2. Recombinant protein control fragment (Product #RP-93782). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649090 |
Product Specific Information
Immunogen sequence:
LLGKVETAKN SLVGPAWQTG LHHLAGPVYI FAITHSLEQP WTTPRSREVA REVLTSLLQV TECGSVAGFL HGENEDEKG
Ortholog sequence identity:
- Mouse: 71%
- Rat: 70%
Target Information
The DNA replication (origin) licensing system is necessary for duplicating the genome in each cell cycle. Geminin is a protein that prevents DNA replication by blocking the MCM complex incorporation into the prereplication complex (pre-RC). It is absent during G1 phase and accumulates during S, G2, and M phases of mitosis. It is then degraded during the metaphase-anaphase transition allowing replication to occur during subsequent cycles. Geminin has also been implicated in maintaining integrity of the male germline genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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