Thermo Fisher Scientific Human Flt-3 Ligand (FLT3L), Animal-Free Recombinant Protein, PeproTech
인체 유래 Flt-3 Ligand(FLT3L) 재조합 단백질로, 동물 유래 성분이 없는 고순도 제품입니다. 인간 AML5 세포 증식을 자극하는 생물학적 활성이 확인되었습니다. 면역세포 분화 및 수지상세포 연구에 적합하며, 상온 배송 및 -20°C 보관이 권장됩니다.
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Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to related publications (56 available)
Miscellaneous PubMed (Misc)
- Refer to related publication (1 available)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Hamster, Human, Mouse, Rabbit |
| Expression System | E. coli |
| Amino Acid Sequence | TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA |
| Molecular Weight | 17.6 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | ED50 ≤ 1.0 ng/ml (specific activity ≥ 1 × 10⁶ units/mg, human AML5 cell proliferation assay) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a protein-coding gene associated with Aplastic Anemia and Brain Cancer.
It plays a key role in:
- Hematopoietic stem cell differentiation and lineage-specific marker pathways
- Ras signaling pathway
- Dendritic cell (DC) development, especially plasmacytoid DCs and CD8⁺ classical DCs
Dendritic cells bridge innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG is particularly important for the differentiation and maintenance of these immune cell subsets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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