Thermo Fisher Scientific DNA Ligase III Polyclonal Antibody
Thermo Fisher Scientific의 DNA Ligase III Polyclonal Antibody는 인간 DNA Ligase III 중간 영역을 표적으로 하는 토끼 유래 IgG 항체입니다. Western blot에 적합하며, 다양한 종에서 높은 상동성을 보입니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human DNA Ligase III (aa 933–982) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690493 |
Product Specific Information
This target displays homology in the following species:
- Dog: 100%
- Guinea Pig: 93%
- Horse: 100%
- Human: 100%
- Mouse: 100%
- Pig: 100%
- Rabbit: 100%
- Rat: 100%
Target Information
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair, and recombination.
DNA Ligase III gene product migrates as a 100 kDa (α-form) protein in somatic tissues, is ubiquitously expressed, and complexes with XRCC-1 and a 97 kDa (β-form) protein found in testis.
DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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