
Thermo Fisher Scientific SYP Monoclonal Antibody (OTI3E2), TrueMAB
Synaptophysin 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC에 적합합니다. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도, PBS/BSA/Glycerol 완충액에 보관됩니다. 신경세포 및 신경내분비 종양 연구용으로 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E2 |
| Immunogen | Full length human recombinant protein of human SYP produced in HEK293T cell. Target Family: Synaptophysin (UniProt ID: P08247-1, Antigen Range: 1–313) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in regulating short-term and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene are associated with X-linked mental retardation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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