Thermo Fisher Scientific PAK5 Polyclonal Antibody
PAK5 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간 PAK5에 반응합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PAK5. Recombinant protein control fragment (Product #RP-88619). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789881 |
Product Specific Information
Immunogen sequence:
KPSEYSDLKW EYQRASSSSP LDYSFQFTPS RTAGTSGCSK ESLAYSESEW GPSLDDYDRR PKSSYLNQTS PQPTMRQRSR SGSGLQEPMM PFGASAFKTH PQGHSYNSYT YPRLSEPTMC IPKVDYDRAQ MVLSP
Target Information
PAK7 (KIAA1264) is implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling.
This kinase contains a CDC42/Rac1 interactive binding motif and binds CDC42 in the presence of GTP.
Predominantly expressed in brain, it promotes neurite outgrowth and may play a role in neurite development.
Associated with microtubule networks, it induces microtubule stabilization.
Subcellular localization is tightly regulated during cell cycle progression.
Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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