Thermo Fisher Scientific HES5 Monoclonal Antibody (OTI6F7), TrueMAB
HES5 단백질을 인식하는 마우스 단일클론 항체로 Western blot에 적합. 인간 종에 반응하며 1 mg/mL 농도의 액상 형태로 제공. Affinity chromatography로 정제되어 높은 특이성 보유. 연구용으로만 사용 가능.
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- TA810555
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F7 |
| Immunogen | Full length human recombinant protein of human HES5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HES5 is a downstream effector of the Notch signaling pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma.
Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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