Thermo Fisher Scientific TAUT Polyclonal Antibody
인간 TAUT 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포 내 타우린 수송 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TAUT. Recombinant protein control fragment (Product #RP-91269) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648241 |
Product Specific Information
- Immunogen sequence: GPFLVRVKYL LTPREPNRWA VEREGATPYN SRTVMNGALV KPTHIIVETM
- Highest antigen sequence identity: Mouse – 78%, Rat – 78%
Target Information
Taurine is an abundant organic osmolyte with antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT), a sodium- and chloride-dependent multi-pass membrane protein of the sodium neurotransmitter symporter (SNF) family. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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