Thermo Fisher Scientific TNFAIP8 Monoclonal Antibody (OTI1H9), TrueMAB
TNFAIP8 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 고순도의 액상 항체로 PBS/BSA/glycerol 용액에 보존되며, -20°C에서 보관합니다. TNFα-IP8 관련 세포사멸 및 종양 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H9 |
| Immunogen | Full-length human recombinant TNFAIP8 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TNFalpha-IP8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2, or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF. Its induction by TNF is dependent on NFkappa B activation. TNFalpha-IP8 negatively regulates apoptosis and may play a role in tumor progression by inhibiting caspase-8 activity, preventing BID cleavage and caspase-3 activation during TNF-mediated apoptosis. It is highly expressed in thymus, bone marrow, lymph node, spleen, thyroid, placenta, and various tumor tissues, as well as in fetal lung, liver, and kidney. TNFalpha-IP8 exists as three isoforms produced by alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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