Thermo Fisher Scientific MRPL12 Polyclonal Antibody
Human MRPL12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, Affinity Chromatography로 정제되었습니다. PBS(2% sucrose) 용액에 0.09% sodium azide 포함, -20°C 보관 권장.
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Applications
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MRPL12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2608565 |
Product Specific Information
- Peptide sequence: KKTLKIQDVG LVPMGGVMSG AVPAAAAQEA VEEDIPIAKE RTHFTVRLTE
- Sequence homology: Dog: 77%; Human: 100%
Target Information
MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein involved in protein synthesis within the mitochondrion.
MRPL12 is enhanced in growth-stimulated cells due to transcriptional activation, suggesting a role as a translational regulator of mitochondrial mRNAs.
Impairment of MRPL12 leads to reduced cell growth rate, decreased mitochondrial ATP production, and loss of oxidative phosphorylation.
It is cleaved during mitochondrial translocation, exists as dimers binding the large ribosomal subunit, and is 198 amino acids in length.
Belongs to the ribosomal protein L12P family and is highly expressed in the colon.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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