Thermo Fisher Scientific CHRNB2 Polyclonal Antibody
Rabbit polyclonal antibody targeting CHRNB2 beta 2 subunit of neuronal acetylcholine receptor. Validated for Western blot in mouse and rat. Antigen affinity purified, unconjugated format. Supplied in liquid form with glycerol buffer, stored at -20°C.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein from the cytoplasmic loop of the beta 2 subunit of rat nAChR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen Affinity Chromatography |
| Storage Buffer | 10 mM HEPES, pH 7.5, with 100 µg/mL BSA, 50% glycerol, 0.15 M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2807444 |
Product Specific Information
Antigen affinity purified from pooled serum.
Target Information
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels that mediate sodium and potassium flow across the plasma membrane in response to ligands such as acetylcholine and nicotine. The CHRNB2 gene encodes one of several beta subunits, and mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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