Thermo Fisher Scientific GAB2 Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF): 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
LSSSSQHLLRE RKSSAPSHSS QPTLFTFEPP VSNHMQPTLS TSAPQEYLYL HQCISRRAEN ARSASFSQGT RASFLMRSDT AVQKLAQGNG HCVNGISGQV HGFYSLPKPS RHNTEFRDST

Highest antigen sequence identity to the following orthologs:

• Mouse: 88%
• Rat: 85%

Target Information

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domains and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors.
The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor.
Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(PA5-64878_GAB2_Q9UQC2-1_Rabbit.svg 및 PA5-64878_GAB2_Q9UQC2-1_Rabbit_PDP.jpeg)