Thermo Fisher Scientific GAB2 Polyclonal Antibody
Human GAB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적 보관 가능.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GAB2 (aa 145–265) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665183 |
Product Specific Information
Immunogen sequence:
LSSSSQHLLRE RKSSAPSHSS QPTLFTFEPP VSNHMQPTLS TSAPQEYLYL HQCISRRAEN ARSASFSQGT RASFLMRSDT AVQKLAQGNG HCVNGISGQV HGFYSLPKPS RHNTEFRDST
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 85%
Target Information
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domains and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors.
The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor.
Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(PA5-64878_GAB2_Q9UQC2-1_Rabbit.svg 및 PA5-64878_GAB2_Q9UQC2-1_Rabbit_PDP.jpeg)
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