Thermo Fisher Scientific PAPD5 Polyclonal Antibody
Thermo Fisher Scientific의 PAPD5 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며, Western blot에 최적화된 검증된 항체입니다. 액상 형태로 제공되며, 고순도의 Ammonium sulfate precipitation 정제 방식과 안정적인 TBS 버퍼로 구성되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HALPAEQRDFLP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933371 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_001035374.2; NP_001035375.2).
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP onto RNA 3′ poly(A) tail, creating a heterogeneous poly(A) tail that stabilizes mRNAs by protecting them from deadenylation (PubMed:21788334, PubMed:30026317). Functions as a catalytic subunit of a TRAMP-like complex involved in post-transcriptional quality control. Polyadenylation with short oligo(A) tails is required for exosome-mediated degradation of nuclear RNA substrates.
Required for cytoplasmic polyadenylation of mRNAs involved in carbohydrate metabolism, including SLC2A1/GLUT1 (PubMed:28383716). Plays a role in replication-dependent histone mRNA degradation and sister chromatid cohesion (PubMed:18172165). Mediates 3′ adenylation of microRNA MIR21 and H/ACA box snoRNAs, enhancing their stability and maturation (PubMed:25049417, PubMed:22442037).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-142725_PAPD5_Q8NDF8-1_Goat.svg
- PA5-142725_PAPD5_Q8NDF8-1_Goat_PDP.jpeg
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