Thermo Fisher Scientific OLFM3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of mouse OLFM3 (NP_6947971) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OLFM3,uniProtId:Q96PB7-1,ncbiNodeId:9606,antigenRange:269-285,antigenLength:478,antigenImageFileName:PA5-110059_OLFM3_Q96PB7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110059_OLFM3_Q96PB7-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:OLFM3,uniProtId:P63056-1,ncbiNodeId:10090,antigenRange:200-300,antigenLength:478,antigenImageFileName:PA5-110059_OLFM3_P63056-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110059_OLFM3_P63056-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.87 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855470

Product Specific Information

Immunogen sequence: HQRVLSLETR LRDCMKKLTC GKLMKITGPI TVKTSGTRFG AWMTDPLASE KNNRVWYMDS YTNNKIVREY KSIADFVSGA ESRTYNLPFK WAGTNHVVYN G

Target Information

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.