Thermo Fisher Scientific DCLK1 Monoclonal Antibody (OTI1F8), TrueMAB
인간 DCLK1 단백질을 표적으로 하는 Mouse monoclonal 항체. Western blot 및 IHC(P) 검증 완료. 1 mg/mL 농도의 액상 형태로 제공되며, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 193–492 of human DCLK1 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
DCAMKL1 (DCLK1) serine/threonine kinase, also known as doublecortin-like kinase 1, contains two N-terminal doublecortin domains that bind microtubules and regulate polymerization, a C-terminal serine/threonine kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase, and a serine/proline-rich domain mediating protein-protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and exhibits microtubule-polymerizing activity independent of its kinase function. It plays roles in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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