Thermo Fisher Scientific DRD2 Monoclonal Antibody (1B11)
DRD2 단백질을 인식하는 Mouse monoclonal antibody(1B11)로 Western blot 및 ELISA에 사용 가능. 인간 시료 반응성. 액상 형태, 보존제 없음. -20°C 보관, 동결/해동 반복 피할 것. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B11 |
| Immunogen | DRD2 (AAH21195, 1 a.a. approximately 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDPLNLSWYD DDLERQNWSR PFNGSDGKAD RPHYNYYATL LTLLIAVIVF GNVLVCMAVS REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW KFSRIHCDIF
Target Information
The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors.
DRD2 may be linked to alcoholism and other substance-use disorders.
Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson’s disease.
Three alternatively spliced isoforms have been identified.
DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord.
ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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