Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, Flow 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:100–1:500 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within mouse TRPM2 aa 100–150/1503 (Cytoplasmic) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913518 |
Product Specific Information
- Positive Control: THP-1 cell lysate, PC-3 cell lysate, rat cerebellum tissue, human bone tissue, mouse brain tissue, SH-SY5Y
- Subcellular Location: Lysosome, cell membrane, perikaryon, cell projection, cytoplasmic vesicle
Target Information
TRPM2 belongs to the ion transport protein family, including sodium, potassium, and calcium ion channels. These proteins possess six transmembrane helices, with the last two flanking a loop determining ion selectivity. TRPM2 is activated by oxidative stress and contributes to susceptibility to cell death. It functions as a calcium-permeable cation channel regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants have been described, though their full-length nature remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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