Thermo Fisher Scientific UBXN2B Monoclonal Antibody (OTI1G3)
UBXN2B 단백질을 인식하는 Thermo Fisher의 단클론 항체. Western blot 및 유세포분석에 최적화됨. 인간 단백질에 반응하며, 액상 형태로 제공. Affinity Chromatography로 정제되어 높은 특이성과 재현성을 보장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G3 |
| Immunogen | Full length human recombinant protein of UBXN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.39 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723762 |
Target Information
UBXN2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain.
UBXN2B is required for ER and Golgi biogenesis and plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis.
Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity.
Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis.
The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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