Thermo Fisher Scientific GABRG1 Polyclonal Antibody
GABRG1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, PBS/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GABRG1 (Accession Q8N1C3), corresponding to amino acid residues S18–L68. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818250 |
Product Specific Information
This antibody detects endogenous levels of GABRG1.
Target Information
Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. It is an integral membrane protein that inhibits neurotransmission by binding to the benzodiazepine receptor and opening a chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4.
GABAA receptors, members of the Cys-loop ligand-gated ion channel family, mediate the inhibitory effects of GABA along with GABAB receptors. Structurally, GABRG1 forms pentameric proteins consisting of five subunits from different families.
Diseases associated with GABRG1 include Alcohol Dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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