Thermo Fisher Scientific alpha Actinin 2 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 alpha Actinin 2 폴리클로날 항체. Western Blot에 적합하며, Affinity chromatography로 정제된 액상 형태. PBS와 50% glycerol 보존액에 0.02% sodium azide 포함. -20°C에서 보관, 연구용 전용.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACTN2 (Accession P35609), corresponding to amino acid residues K38–D88 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899457 |
Product Specific Information
This antibody detects endogenous levels of total ACTN2.
Target Information
Alpha actinins belong to the spectrin gene superfamily, representing a diverse group of cytoskeletal proteins, including alpha and beta spectrins and dystrophins.
Alpha actinin is an actin-binding protein with multiple roles in different cell types.
- In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it binds actin to the membrane.
- In skeletal, cardiac, and smooth muscle, isoforms are localized to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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