Thermo Fisher Scientific HPD Polyclonal Antibody
HPD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human HPD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636697 |
Product Specific Information
This antibody detects endogenous levels of total HPD protein.
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif essential for their anti-apoptotic activity. A mitochondrial serine protease, Omi/HtrA2, is released upon apoptotic induction and binds to IAP. Similar to Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. Deregulated cytoplasmic expression of Omi induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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