Thermo Fisher Scientific RORB Monoclonal Antibody (OTI3D7), TrueMAB
인간 RORB 단백질(aa 1-260)을 면역원으로 제작된 Mouse IgG3 단클론 항체. Western blot에 1:2,000 희석으로 검증됨. 액상형, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 중추신경계 발달 및 생체 리듬 관련 RORβ 단백질 연구용.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human RORB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Retinoid-related orphan receptor beta (RORβ), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing.
Disruption of RORβ in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility.
RORβ binds to monomeric response elements containing the sequence AnnTAGGTCA as a monomer.
An alternatively spliced isoform, RORβ2, is confined to the pineal gland and retina.
RORβ2 shares common DNA- and ligand-binding domains with wild-type RORβ but differs in its amino-terminal domain.
Expression of RORβ has been documented in various regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: TA806860_RORB_Q92753-2_House_mouse_PDP.jpeg)
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