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ELK Biotechnology E2F-1 (Acetyl Lys120) rabbit pAb
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E2F-1 (Acetyl Lys120) rabbit pAb는 인간, 마우스, 랫트에서 반응하는 폴리클로날 항체로 세포핵 내 E2F-1 단백질의 아세틸화 상태를 검출합니다. WB 및 ELISA에 적합하며 고특이성과 안정적인 결합력을 제공합니다.
- 판매단위
- pk
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ELK Biotechnology ES8446-100UL E2F-1 (Acetyl Lys120) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES8446-50UL E2F-1 (Acetyl Lys120) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology E2F-1 (Acetyl Lys120) rabbit pAb
제품명
E2F-1 (Acetyl Lys120) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | E2F1, RBBP3 |
| Applications | WB, ELISA |
| Recommended Dilutions | WB: 1:500–10,000; ELISA: 1:10,000 |
| Immunogen | Synthesized acetyl-peptide from human protein (AA range: 100–170) |
| Species Reactivity | Human: K120; Mouse: K115; Rat: K118 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| GeneID (Human) | 1869 |
| Human Swiss-Prot No. | Q01094 |
| Cellular Localization | Nucleus |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of the cell cycle and the action of tumor suppressor proteins, and is also a target of transforming proteins of small DNA tumor viruses.
E2F proteins contain several evolutionarily conserved domains, including:
- DNA binding domain
- Dimerization domain (interacts with DP transcription factors)
- Transactivation domain enriched in acidic amino acids
- Tumor suppressor protein association domain (embedded within the transactivation domain)
E2F-1, along with E2F2 and E2F3, possesses an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein (pRB) in a cell-cycle dependent manner.
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