ELK Biotechnology Histone H3 (Di Methyl Lys27) rabbit pAb
Histone H3 (Di Methyl Lys27) rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 폴리클로날 항체로, 핵 및 염색체 내 히스톤 H3의 K27 이중 메틸화 부위를 검출합니다. Western blot과 ELISA에 적합하며, 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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Histone H3 (Di Methyl Lys27) rabbit pAb
제품 개요
Histone H3 (Di Methyl Lys27) rabbit pAb는 인간 Histone H3의 K27 이중 메틸화 부위를 인식하는 폴리클로날 항체입니다. 핵 및 염색체 내 히스톤 구조 연구에 사용되며, Western blot 및 ELISA 분석에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Di Methyl Lys27) rabbit pAb |
| Alternative Names | H3K27ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; H3F3A; H3F3B; H3F3C; Histone H3.1; Histone H3.2; Histone H3.3; Histone H3.5 등 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000, ELISA: 1/10000 (다른 응용은 미시험) |
| Immunogen | Synthesized peptide derived from human Histone H3 around the di-methylation site of K27 |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 8350 |
| Human Swiss-Prot No | P68431 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone (H1) with the DNA between nucleosomes to form higher-order chromatin structures. The gene encoding Histone H3 is intronless and replication-dependent, lacking polyA tails and containing a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22-p21.3.
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