ELK Biotechnology ADAMTS-18 rabbit pAb
ADAMTS-18 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능. 세포외 기질 단백질 분석에 적합하며, 135kDa 밴드 검출. Human 및 Mouse 시료에 반응.
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ADAMTS-18 rabbit pAb
제품 개요
ADAMTS-18 단백질을 인식하는 토끼 다클론 항체입니다. ADAMTS 계열 단백질은 세포외 기질에서 다양한 생리적 기능을 수행하며, 종양 억제 및 혈액응고 조절과 관련이 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | ADAMTS-18 rabbit pAb |
| Alternative Names | ADAMTS18; ADAMTS21; A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/10000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from ADAMTS-18 (AA range: 1030–1110) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 135 kDa |
| Gene ID (Human) | 170692 |
| Human Swiss-Prot No | Q8TE60 |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [Provided by RefSeq, May 2016]
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