
ELK Biotechnology BMP-2 rabbit pAb
BMP-2 rabbit pAb는 TGF-beta 슈퍼패밀리 단백질을 인식하는 다클론 항체로, IF, WB, IHC, ELISA 등 다양한 면역실험에 적합합니다. 뼈와 연골 발달 관련 연구에 유용하며, 고순도 IgG 폴리클론 항체로 안정적인 신호 검출을 제공합니다.
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제품명
BMP-2 rabbit pAb
대체 명칭
BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A
적용 분야
- IF (Immunofluorescence)
- WB (Western Blot)
- IHC (Immunohistochemistry)
- ELISA
권장 희석 배율
| 실험 종류 | 희석 배율 |
|---|---|
| IF | 1:50–200 |
| WB | 1:500–1:2000 |
| IHC-p | 1:100–1:300 |
| ELISA | 1:10000 |
| Other applications not yet tested. |
면역원 (Immunogen)
Synthesized peptide derived from Bone morphogenetic protein 2 (AA range: 341–390)
보관 조건
- -20°C, 1년 안정
항체 정보
| 항목 | 내용 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| 농도 | 1 mg/ml |
| Observed Band | 44 kD |
| GeneID (Human) | 650 |
| Human Swiss-Prot No | P12643 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Mouse, Rat |
배경 (Background)
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
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