
ELK Biotechnology CKR-6 rabbit pAb
CCR6(CKR-6)에 특이적인 rabbit polyclonal antibody로, 인간·쥐·마우스 시료에 반응합니다. WB 및 ELISA에 사용 가능하며, 세포막 단백질 검출에 적합합니다. N-말단 합성 펩타이드로 면역화되어 높은 특이성과 재현성을 제공합니다.
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제품명
CKR-6 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CCR6; CKRL3; CMKBR6; GPR29; STRL22; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD196 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000; ELISA: 1/10000; Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the N-terminal region of human CCR6 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kD |
| GeneID (Human) | 1235 |
| Human Swiss-Prot No. | P51684 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein; Cell surface |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3α). This receptor plays a role in B-lineage maturation and antigen-driven B-cell differentiation, and may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants encoding the same protein have been described for this gene.
[provided by RefSeq, Jul 2008]
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