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ELK Biotechnology Cdc25A (phospho Ser178) rabbit pAb
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Cdc25A 단백질의 Ser178 인산화 부위를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 세포 주기 조절 연구에 활용되며, 인체, 마우스, 랫트 시료에 반응합니다. -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
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ELK Biotechnology ES8130-100UL Cdc25A (phospho Ser178) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES8130-50UL Cdc25A (phospho Ser178) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Cdc25A (phospho Ser178) rabbit pAb
Cdc25A (phospho Ser178) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cdc25A (phospho Ser178) rabbit pAb |
| Alternative Names | CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser178 (AA range: 144-193) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 59 kD |
| Gene ID (Human) | 993 |
| Human Swiss-Prot No. | P30304 |
| Cellular Localization | Intracellular, nucleus, nucleoplasm, cytoplasm, cytosol |
| Species Reactivity | Human; Mouse; Rat |
Background
Cell division cycle 25A (CDC25A) is a member of the CDC25 family of phosphatases and is required for progression from G1 to S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, preventing cells with chromosomal abnormalities from progressing through cell division. CDC25A functions as an oncogene, though its exact role in oncogenesis has not been fully elucidated. Two transcript variants encoding different isoforms have been identified for this gene (RefSeq, Jul 2008).
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