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ELK Biotechnology Sec16A rabbit pAb
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ELK Biotechnology Sec16A rabbit pAb

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Sec16A 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 적합합니다. 인간 SEC16A 유래 펩타이드로 면역화되었으며, ER-Golgi 단백질 수송 연구에 활용됩니다. -20°C에서 1년 보관 가능하며, Human, Rat, Mouse에 반응합니다.

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ELK Biotechnology ES8126-100UL Sec16A rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES8126-50UL Sec16A rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Sec16A rabbit pAb

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Sec16A rabbit pAb

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항목 내용
Alternative Names SEC16A; KIAA0310; SEC16; SEC16L; Protein transport protein Sec16A; SEC16 homolog A
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
ELISA: 1/20000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human SEC16A (AA range: 1013–1062)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Gene ID (Human) 9919
Human Swiss-Prot No. O15027
Cellular Localization Endoplasmic reticulum membrane; Peripheral membrane protein; Golgi apparatus membrane; Cytoplasm (perinuclear region, cytosol); Microsome membrane.
SAR1A activity is required to maintain SEC16A localization at discrete locations on the ER membrane, perhaps by preventing its dissociation (PubMed:17192411). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). MIA3 and LRRK2 are required for its proper localization to ERES (PubMed:25201882, PubMed:28442536, PubMed:19638414, PubMed:17428803, PubMed:22355596). Recruited to microsomal membrane in SAR1-dependent manner (PubMed:17428803).
Background This gene encodes a protein that forms part of the Sec16 complex. It plays a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants encoding different isoforms. (RefSeq, Feb 2013)
Species Reactivity Human; Rat; Mouse

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