Thermo Fisher Scientific CD4 Monoclonal Antibody (RM4-5)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Flow Cytometry (Flow)

Assay-dependent

View 44 publications 44 publications

Miscellaneous PubMed (Misc)

-

View 5 publications 5 publications

Product Specifications

Published species

Mouse

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

RM4-5

Immunogen

Mouse CD4

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Alexa Fluor 405
• APC
• APC-Cyanine5.5
• Pacific Blue
• Pacific Orange
• PE-Texas Red
• Qdot 605
• Qdot 800
• TRI-COLOR
• Request custom conjugation

Form

Liquid

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10373815

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.