Thermo Fisher Scientific ACAT2 Recombinant Rabbit Monoclonal Antibody (6Z5L1)
ACAT2 단백질을 인식하는 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, HEK293 세포에서 발현된 재조합 항체입니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6Z5L1 |
| Immunogen | A synthetic peptide corresponding to amino acids 150–250 of human ACAT2 (UniProt ID: Q9BWD1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911809 |
Product Specific Information
- Positive test controls: HeLa, SW620, HepG2, Mouse liver, Mouse brain, Mouse kidney, Rat brain, Rat kidney
- Subcellular localization: Cytoplasm
- Immunogen sequence:
GLTDAFHNCH MGITAENVAK KWQVSREDQD KVAVLSQNRT ENAQKAGHFD KEIVPVLVST RKGLIEVKTD EFPRHGSNIE AMSKLKPYFL TDGTGTVTPA N
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The encoded protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, it lacks a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, inhibiting oncogenic transformation, cell proliferation, and apoptosis suppression. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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