Thermo Fisher Scientific GNG8 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GNG8 protein. Validated for Western blot with human, mouse, and rat samples. Supplied as liquid, 1 mg/mL in PBS with 30% glycerol. Suitable for research use only, stored at -20°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: Not specified
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human GNG8 (amino acids 47–70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691950 |
Product Specific Information
Predicted to react with mouse and rat samples.
Target Information
Heterotrimeric G proteins relay information from cell surface receptors to intracellular effectors. Each receptor detects specific extracellular stimuli such as photons, pheromones, odorants, hormones, or neurotransmitters, while effectors like adenyl cyclase generate intracellular messengers.
In mammals, G protein α, β, and γ subunits are encoded by at least 16, 4, and 7 genes, respectively. While α subunits have been most studied for their GTP-binding and hydrolysis activity, βγ subunits also play important regulatory roles. Different tissue-specific G protein complexes contain distinct γ, α, and β subunits, allowing for functional diversity through preferential subunit associations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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