Thermo Fisher Scientific GCAT Polyclonal Antibody
GCAT 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 170–419 of human GCAT (NP_0551061) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.67 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806199 |
Product Specific Information
Immunogen sequence:
KAHKYRYRHL DMADLEAKLQ EAQKHRLRLV ATDGAFSMDG DIAPLQEICC LASRYGALVF MDECHATGFL GPTGRGTDEL LGVMDQVTII NSTLGKALGG ASGGYTTGPG PLVSLLRQRA RPYLFSNSLP PAVVGCASKA LDLLMGSNTI VQSMAAKTQR FRSKMEAAGF TISGASHPIC PVMLGDARLA SRMADDMLKR GIFVIGFSYP VVPKGKARIR VQISAVHSEE DIDRCVEAFV EVGRLHGALP
Positive Samples: Mouse eye
Cellular Location: Mitochondrion, Nucleus
Target Information
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase.
L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase.
GCAT is the second enzyme in this pathway, catalyzing the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA.
The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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