Thermo Fisher Scientific Histone H3.3B Polyclonal Antibody
Rabbit polyclonal antibody specific for Histone H3.3B. Validated for ICC/IF with high specificity to human samples. Supplied as liquid, affinity-purified, and unconjugated. Ideal for chromatin research and histone modification studies.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 38–64). Recombinant protein control fragment: RP-110243 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092115 |
Product Specific Information
- Immunogen sequence: KPHRYRPGTV ALREIRRYQK STELLIR
- Antigen sequence identity: Mouse 100%; Rat 100%
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with other core histones, it forms nucleosomes that package DNA. Histones are crucial for transcription regulation, DNA repair, replication, and chromosomal stability.
The N-terminal tail of histone H3 undergoes various post-translational modifications, including methylation, acetylation, and phosphorylation, which influence chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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