ELK Biotechnology SNTA1 rabbit pAb

제품명

SNTA1 rabbit pAb

제품 설명

SNTA1 단백질을 인식하는 토끼 폴리클로날 항체입니다. 인간 및 생쥐 시료에서 사용 가능하며, 웨스턴블롯(WB)과 면역조직화학(IHC)에 적합합니다. 세포막, 세포골격, 신경근 접합부 등에서의 SNTA1 단백질 발현 연구에 활용됩니다.

제품 사양

Background

Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues.
The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b complex in cardiomyocytes.
This gene is a susceptibility locus for Long-QT syndrome (LQT) and sudden infant death syndrome (SIDS). It also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and affects intracellular calcium ion levels in muscle tissue.
(Provided by RefSeq, Jan 2013)