ELK Biotechnology SODE rabbit pAb
SODE 단백질을 인식하는 토끼 폴리클로날 항체로, WB, ELISA, IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 IgG 형식으로 제공되며, -20°C에서 1년 보관 가능. 산화 스트레스 연구 및 SOD 관련 단백질 분석에 적합.
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제품 개요
ELK Biotechnology SODE rabbit pAb는 인간 SODE 단백질의 특정 펩타이드 서열(AA 67-117)을 면역원으로 제작된 토끼 폴리클로날 항체입니다. 본 항체는 WB, ELISA, IHC 등 다양한 응용에 적합하며, 산화 스트레스 및 SOD 관련 연구에 유용합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | SODE rabbit pAb |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human SODE (AA range: 67–117) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 6649 |
| Human Swiss-Prot No. | P08294 |
| Cellular Localization | Secreted, extracellular space, Golgi apparatus, trans-Golgi network. 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein (type C subunit) exhibit high affinity for heparin and are anchored to the ECM, while those consisting of a proteolytically cleaved form (type A subunit) exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk.
[provided by RefSeq, Oct 2015]
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