ELK Biotechnology SRGP2 rabbit pAb
SRGP2 단백질을 인식하는 토끼 다클론 항체로 WB 실험에 적합. 인간, 생쥐, 랫트 시료에서 반응. 합성 펩타이드(AA 476-526) 면역원 사용. -20°C에서 1년 보관 가능. Rac1 GTPase 활성 조절 및 신경 발달 연구에 유용.
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SRGP2 rabbit pAb
공급업체: ELK Biotechnology
제품명: SRGP2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human SRGP2 (AA 476–526) |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 23380 |
| Human Swiss-Prot No | O75044 |
| Species Reactivity | Human, Mouse, Rat |
세포 내 위치 (Cellular Localization)
Cell membrane; cell projection (dendritic spine); cell junction (synapse, postsynaptic density); postsynaptic cell membrane; lamellipodium; cytoplasmic vesicle (phagosome); nucleus; cytoplasm (cytosol).
Recruited to actin-rich phagosomes during phagocytosis (By similarity).
Translocates from nucleus to cytoplasm during development (By similarity).
배경 (Background)
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family.
The encoded protein stimulates GTPase activity of Rac1 and plays a role in cortical neuron development.
This locus has several paralogs on human chromosome 1 resulting from segmental duplication.
While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes.
Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]
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