ELK Biotechnology STAR5 rabbit pAb
STAR5 단백질을 인식하는 토끼 다클론 항체로, WB, ELISA, IHC에 적합합니다. 인간 및 생쥐 시료에 반응하며, -20°C에서 1년간 보관 가능합니다. 세포 내 콜레스테롤 운반 관련 연구에 유용합니다.
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제품명
STAR5 rabbit pAb
제품 개요
ELK Biotechnology의 STAR5 rabbit polyclonal antibody는 인간 및 생쥐 시료에서 STAR5 단백질을 검출하기 위한 항체입니다. 세포 내 콜레스테롤 및 지질 운반 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB, ELISA, IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human STAR5 (AA range: 129–179) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 80765 |
| Human Swiss-Prot No. | Q9NSY2 |
| Cellular Localization | Mitochondrion, Cytosol |
| Species Reactivity | Human, Mouse |
배경 (Background)
Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes.
This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol.
Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus.
Alternative splicing of this gene produces multiple transcript variants. [Provided by RefSeq, Jan 2016]
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