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ELK Biotechnology TBK1/NAK (phospho-Ser172) rabbit pAb
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TBK1/NAK (phospho-Ser172)을 인식하는 rabbit polyclonal antibody로, NF-κB 신호전달 연구에 적합. WB에 사용 가능하며, 1:1000~2000 희석 권장. Human 및 Mouse 반응성. -20°C에서 1년 보관 가능.
- 판매단위
- pk
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ELK Biotechnology ES12793-100UL TBK1/NAK (phospho-Ser172) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES12793-50UL TBK1/NAK (phospho-Ser172) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology TBK1/NAK (phospho-Ser172) rabbit pAb
제품명
TBK1/NAK (phospho-Ser172) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Serine/threonine-protein kinase TBK1 (EC 2.7.11.1), NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1 |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human TBK1 and NAK (Ser172) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 80 kD |
| Gene ID (Human) | 29110 |
| Human Swiss-Prot No. | Q9UHD2 |
| Cellular Localization | Cytoplasm. Upon mitogen stimulation or immune system triggering, TBK1 is recruited to the exocyst by EXOC2. |
| Species Reactivity | Human, Mouse |
Background
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
[provided by RefSeq, Oct 2010]
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