ELK Biotechnology TCPR2 rabbit pAb
TCPR2 단백질을 인식하는 토끼 폴리클로날 항체로 WB 분석에 적합합니다. 인간, 랫, 마우스 시료에 반응하며 자가포식 관련 연구에 활용 가능합니다. -20°C에서 1년 보관 가능하며, 고순도 IgG 항체입니다.
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TCPR2 rabbit pAb
제품 개요
TCPR2 rabbit pAb는 인간 TCPR2 단백질을 인식하는 토끼 폴리클로날 항체로, 자가포식 및 신경질환 관련 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | TCPR2 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human TCPR2 (AA range: 598–648) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 9895 |
| Human Swiss-Prot No | O15040 |
| Species Reactivity | Human, Rat, Mouse |
Background
The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP), characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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