Thermo Fisher Scientific GMFB Polyclonal Antibody
GMFB 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot과 IHC(Paraffin)에 적합합니다. 인간 및 마우스 시료에 반응하며, 신경계 관련 연구와 BDNF 발현 연구에 활용됩니다. 항원 친화 크로마토그래피로 정제되었습니다.
- 카탈로그번호
- PA551220
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human GMFB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636668 |
Product Specific Information
This antibody detects endogenous levels of total GMFB protein.
Target Information
GMFB (Glia Maturation Factor Beta) is a protein phosphorylated following phorbol ester stimulation and plays a key role in the nervous system. It promotes brain cell differentiation, stimulates neural regeneration, and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes enhances brain-derived neurotrophic factor (BDNF) production. GMF expression increases with exercise and is essential for exercise-induced BDNF production, contributing to neuroprotection. In thymoma, GMF produced by tumor cells helps maintain T-cell development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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