Thermo Fisher Scientific USP36 Monoclonal Antibody (OTI9F5), TrueMAB
USP36 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot 및 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 성체 줄기세포 유지 및 전사 억제 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 589–972 of human USP36 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
USP36 may be required for maintaining multiple types of adult stem cells.
It may function as a transcriptional repressor by continuously deubiquitinating histone H2B at promoters of genes critical for cellular differentiation, thereby preventing histone H3 Lys-4 trimethylation (H3K4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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