Thermo Fisher Scientific Ephrin B3 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, mouse hippocampus, rat hippocampus
• Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Cat (100%), Pig (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

EFNB3, a member of the ephrin gene family, is important in brain development and maintenance. EFNB3 expression is particularly high in several forebrain subregions, suggesting a pivotal role in forebrain function.
EPH and EPH-related receptors form the largest subfamily of receptor protein-tyrosine kinases, mediating developmental events in the nervous system.
Ephrin ligands and receptors are categorized by the Eph Nomenclature Committee (1997):

• Ephrin-A (EFNA) class: anchored to the membrane via glycosylphosphatidylinositol linkage
• Ephrin-B (EFNB) class: transmembrane proteins
  Eph receptors are divided into two groups based on extracellular domain sequence similarity and ligand binding affinity.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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